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Bovine Lung APROTININ, 10 mg

Product ID: 10625627

Description

For internal research use only. Products are not intended for diagnostic use, any in vivo applications or resale.

APROTININ from bovine lung can be used for the isolation of proteins as well as for biopharmaceutical downstream purification to inhibit undesired proteolytic activity of serine proteases such as trypsin, plasmin, trypsinogen, urokinase, chymotrypsin, kallikrein, elastase and others.The stability of the Aprotinin molecule is due to the 3 disulfide bonds linking the 6 cysteine members of the chain (Cys5-Cys55, Cys14-Cys38 and Cys30-Cys51). The lysine (15)-alanine (16) sequence on this strongly basic polypeptide represents the active centerMyBioSource BOVINE LUNG APROTININ available in bulk quantities. Custom fills of bovine lung aprotinin available. Custom buffers available on bovine lung Aprotinin on bulk orders.Aprotinin from bovine lung can also be used during immunodiffusion, radioimmunoassay or enzyme-linked immuno assay procedures. Aprotinin is used in chromogenic assays for the determination of antithrombin III, heparin, a2-macroglobulin, factor Xa and thrombin to inhibit disturbing kallikrein or plasmin activities.What is Bovine Aprotinin:A single chain polypeptide isolated from bovine lung with antifibrinolytic and anti-inflammatory activities. As a broad-spectrum serine protease inhibitor, aprotinin bovine competitively and reversibly inhibits the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activator, and tissue and leukocytic proteinases, resulting in attenuation of the systemic inflammatory response (SIR), fibrinolysis, and thrombin generation. This agent also inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. Bovine Aprotinin REF: National Cancer Society/bovine/aprotinin.FREE 8GB USB Flash Drive with the purchase of this item.

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